Menopause symptoms. Climacteric, hormone replcement concept. Mature women hold hands symbolizin female genital organs. Middle aged lady flat vector illustration

Bioidentical Hormone Replacement Therapy

BHRT, which is short for Bio-Identical Hormone Therapy, is a treatment that uses natural hormones to improve your health and wellbeing. It is a therapy used to restore your hormone levels to the normal healthy levels you had in your 20's, but have declined as a result of aging and other reasons. BHRT pellets are made up of the same estrogen and testosterone that's naturally occurring in your body, created from plant-based ingredients. Once the pellets are placed into the subcutaneous fat, then immediately begin releasing a continuous amount of hormones into your bloodstream to restore balance. The procedure typically takes 10-15 minutes and you are able to go back to normal activities within a week. 

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What causes low hormones in women?

The most common cause of low hormones in women is menopause. As a woman ages, there is decreased secretion of estrogen, progesterone, and testosterone from the pituitary gland, adrenal glands, and ovaries. Menopause typically occurs between the ages of 45 and 55 years old and results in the abrupt decline of these hormones, which are essential for the mental and physical well-being of women. There are other causes of low hormones, including premature ovarian failure, excessive exercise or extreme dieting, eating disorders, autoimmune conditions, and surgical removal of the ovaries. 

What are the symptoms of low hormones?

The symptoms of low hormones can vary depending on the person and be differentiated based on the hormone involved:

Low estrogen symptoms: 

  • Hot flashes
  • Night sweats
  • Changes in or cessation of menstruation
  • Vaginal dryness or pain during intercourse
  • Difficulty sleeping and insomnia
  • Changes in mood
  • Increased risk of depression and anxiety
  • Bladder problems such as difficulty urinating, increased need to urinate, and bladder incontinence

Low testosterone symptoms:

  • Decreased sexual desire and libido
  • Difficulty reaching orgasm
  • Fatigue
  • Lack of concentration
  • Muscle weakness
  • Weight gain
  • Thinning hair
  • Increased incidence of cardiovascular disease
  • Loss of bone mineral density
  • Cognitive decline and increased risk of cognitive disorders such as Alzheimer’s disease

What are the benefits of hormone supplementation in women?

There are numerous benefits of testosterone supplementation in women, which have been proven in high quality clinical trials over the last several decades:

  • Improved libido and desire: the same effect we see in men
  • Protective against depression and anxiety: women with low testosterone had a significantly higher rate of depression and anxiety compared to women who were on testosterone supplementation
  • Protective against breast cancer: women with low testosterone had a significantly higher incidence of breast cancer compared to women who were on testosterone supplementation
  • Patients on testosterone therapy for 12 months experience a 5-8% increase in bone mineral density
  • Decreased migraines caused by low testosterone
  • Increased lean muscle mass
  • Decreased body fat
  • Decreased triglycerides, low-density lipoproteins (LDLs), and cholesterol 
  • Decreased risk of cardiovascular events like heart attack: the same effect we see in men 
  • Both testosterone and estrogen have a neuroprotective role against cognitive decline and cognitive disorders

These are the benefits of estrogen supplementation in women:

  • Improvement in hot flashes and night sweats
  • Improvement in insomnia
  • Decreased vaginal dryness and pain during intercourse
  • Decreased migraines caused by low estrogen
  • Improved mood and decreased irritability
Play Video

Dr. Itri discusses the benefits of testosterone supplementation in women

What are Bio-Identical Hormone Pellets?

Bio-Identical Hormone pellets are the size of a grain of rice (or smaller) and are made of the same testosterone and estrogen that occur in your body, not the synthetic forms of estrogen and testosterone that are in other preparations. One of the benefits of the bio-identical form is that the synthetic forms can have side effects such as increased risk of deep vein thrombosis and pulmonary embolism with oral estrogens and allergic reaction to injectable testosterones. Another benefit of the pellets is that patients experience slow, controlled release over months rather than the daily and weekly variation that come with the other routes of administration. The resulting blood level of hormone is also much more predictable with the pellets, peaking at 4-6 weeks after pellet placing and slowly decreasing over 3-4 months. 

Why does my regular doctor tell me not to do hormone replacement with bio-identical pellets?

If you’ve gone to your primary care or gynecology doctor and asked about hormone replacement therapy (HRT), this is likely the response you received:

“I don’t believe in hormone supplementation for women”

“There’s no data to support hormone supplementation in women”

“Our organization doesn’t advocate for hormone supplementation in women”

If you’ve told your gynecology doctor that you have a low libido and desire, it’s likely they told you:

“You should see a sex therapist”

These are the most common responses we hear from female patients who come to us to ask about HRT and hormone supplementation. 

Part of the problem is that these physicians do not differentiate between the types of hormone preparations such as creams, pills, injections, and bio-identical pellets. For example, oral estrogen supplementation significantly increased the risk of thromboembolic events (deep vein thrombosis and pulmonary embolism) because it is a synthetic preparation that is ingested, whereas bio-identical estrogen is identical to the estrogen your body produces and has been shown to NOT increase the risk of thromboembolic events. Pellets are the preferred method at Studio R Aesthetics because they do not cause the same problems as the other preparations. 

Another part of the problem is research studies such as the Women’s Health Initiative (WHI) study, which showed a higher risk for breast cancer, stroke, cardiovascular disease, and thromboembolic events with combined treatment of ONLY synthetic estrogens and progestin (not testosterone or bio-identical hormone pellets).  Since this study, there have been numerous clinical studies evaluating bio-identical hormone pellets, which have been shown to reduce the risk of breast cancer, stroke, and cardiovascular disease in women undergoing hormone supplementation compared to women who were low hormone and not supplemented.  

What is the process for undergoing hormone supplementation?

  • Call us at (434) 260-1667 to schedule a consultation with one of our physicians or click the Book Now button below
  • Complete medical intake forms using our online portal
  • Meet with one of our physicians to review your medical history, symptoms and health concerns, as well as discuss the benefits of hormone supplementation and treatment options. 
  • We use the SottoPelle algorithm for dosing, which incorporates your symptoms and lab results to determine the optimal dose of hormones to bring you back to normal healthy levels
  • Pellets are placed in the office; the procedure takes 10-15 minutes.
  • You will start the feel the benefits of the hormones 3-4 weeks after pellet placement
  • Labs are obtained 5-6 weeks after pellet placement to ensure optimal levels. If you continue to have symptoms despite increased hormone levels, our physicians can place additional pellets. 
  • Pellets typically last 3-4 months and repeat labs are obtained 14-16 weeks after the initial pellet placement to guide subsequent doses.  
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Women's Hormone Replacement

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Christina Shifflett
November 24, 2023

I recently received my first platinum hydrafacial done by Michelle and it was absolutely phenomenal! She took her time and really focused on making it an incredible experience, one of the most relaxing things I have ever done! Not to mention my skin looks and feels amazing!! I will be recommending this to everyone I know and I will absolutely be back for more!

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Jordan Stang
November 11, 2023

Today was my first Hydrafacial done by Michelle! Studio R Aesthetics exceeded my expectations. The staff was extremely nice, the office was adorable and I was very comfortable. My facial was very relaxing. Michelle was terrific, Answered all of my questions and my skin felt amazing afterward. I already can’t wait for my next experience at Studio R Aesthetics. I can not recommend them enough.

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Latasha Breckenridge
October 24, 2023

I had a brow wax and tint. Not only did my brows look AMAZING but I never had someone rub the area around my brows! It was the most calming and relaxing experience! 10/10 recommend!

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Leysa Sallie-Hall
October 21, 2023

I had a awesome experience last week with Studio R Aesthetics, first thing was just how amazing the inside of the building was, it was gorgeous and full of light, so comfortable. I was shocked when I found out about all of the services that they provide, so many! Very impressive! I was also impressed by my doctor- Dr.Segura was a delight and very professional but down-to-earth , I felt very comfortable telling her my issue's she made me feel like I was being heard when I was speaking of my problem with my hair thinning, and falling out drastically, I got a bit emotional talking about my hair and she just made me feel like she really understood what I was going through, it was an amazing experience and I definitely will be going back for a long,long time. Thank you Dr. Segura for your kindness and your compassion for me, you are very special.

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Christina Kim
October 19, 2023

Brandy was great and knowledgeable!!

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Trevor and Taylor H
October 16, 2023

Had a great experience with Dr. Segura! She is very knowledgeable and reassuring. All of the staff were friendly and professional.

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Skylar Coates
October 14, 2023

Amazing practice! Both doctors and staff are very knowledgeable and skilled at what they do! I look forward to every appointment!

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Katie Dockter
October 13, 2023

Michelle did a wonderful job! Thank you Studio R!

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Sylvia Trueman
October 10, 2023

I’ve been a patient of Dr. Segura for a year now, and I’ve had several procedures done by Brandi. Her calm and caring demeanor always brings me great comfort when she can sense my insecurities and difficulty in talking about the things I would like to improve or change. To her, I am the most important person in the world while I’m in her care, she goes into great detail of all procedures, and what they entail. She is very patient, kind and has my best interest in mind at every consultation. She is truly an artist and has given my beauty, and confidence back both inside and out. ❤️ Can’t wait for my next treatment!

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Lawrence Conell
October 7, 2023

Good experience! As a traditional medical person I was a little leery of the spa like setting for what I felt was more of a medical procedure (bioidentical hormone treatment). However, I was treated very professionally by Dr. Itri, who I found to be knowledgeable, competent, and very forthcoming and accommodating in responding to my questions & concerns.

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SIDNEY BLAIR
October 6, 2023

I love coming here! I’ve been seeing Brandy & Michelle for about 3 years. They are so sweet and personable! The studio is GORGEOUS and the whole staff is talented! Highly recommend coming to see them for all of your aesthetic needs!!

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Mary Ashley Cook
October 4, 2023

They were able to get me in same day! Excellent customer service and beautiful office❤️

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Jenna Joseph
October 2, 2023

I started semaglutide in April and finished in August. I went from 171lbs to 133lbs and couldn’t be happier. Everything was so easy, everyone on staff was incredibly kind, and I am so glad I invested in myself. Well worth the money! Thank you, Studio R!

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strykr strykr
September 28, 2023

My name is Matt Street. I have been a client and patient with Studio R for well over a year. Over this time, I have used many of the services provided by Dr. Segura, and Dr. Itri. All of the services have been top-notch. Recently, I received a hydro-facial from Michelle. To say it was an amazing and invigorating experience would be an understatement. Michelle uses cutting edge technology to meticulously treat the face and neck area. I typically get about 3-4 facials a year and Michelle is, by far, the best to ever do it. Her expertise includes deep knowledge on how to maintain healthy skin. She provided me with many cost-effective options to continue to maintain a healthy skin routine. I highly recommend Michelle for all your facial needs. I will be exclusively using her services going forward. Thanks, Matt

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Kim and Jim Mason
September 22, 2023

Jason and Brandi are the experts in promoting optimal health. They understand bioidentical hormone replacement inside and out!! If you're showing the signs of aging: tired, achy, lack of libido, etc. call them right now! They can help you get your vitality back!

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Summer Layton
September 22, 2023

Dr. Segura is one of the kindest, most patient, and skilled physicians I have seen in all my years receiving fillers and Botox. I have not been happy in the past with the results of tox and fillers from others. Dr. Segura has made such a difference in how I feel. Definitely do not pay attention to the very few negative received as I can only assume they are from her competitors.

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Jennifer
September 11, 2023

Dr. Segura exceeded all of my expectations from start to finish. I simply cannot recommend her enough for the most thorough, professional and impressive results.

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Jillian Loughran
September 11, 2023

Dr. Segura and the team are so thorough. She took her time explaining every option and providing a breakdown of cost, time, healing, etc. Will definitely come again.

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Tiarra Young
September 11, 2023

I had a facial done by Michelle she done fantastic. And I had botex by Dr segura very informative and gentle. Definitely will be a repeat customer!!!

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Robert Hicks
September 5, 2023

Outstanding service. It was my first time doing this and Michelle was great! She answered all my questions and I learned a lot during the sugaring!

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Zeljka Peric Zorc
September 4, 2023

My eyebrows have never looked as good as when Michelle does it! She listens and does exactly what you want!

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Terrie Wood
August 29, 2023

I have been a client here for over a year now. I recall my first visit with Dr. Segura and how nervous and intimidated I was. Not for long though! Her quiet, calm and confident manner set me at ease and assured me that I was at the right place and in the right hands. The professional team at Studio R are so friendly and customer focused. I’m not even sure how I came to find them but I am certainly glad I did!!

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Mackenzie Fredricks
August 26, 2023

Dr. Segura was so kind and informative. She took her time to explain everything to me and even made some recommendations based on my goals.

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Shannon Beasley
August 26, 2023

Michele is a very talented aesthetician who has taken a great deal of time educating me about all of the options that align with my skin care goals for aging and sensitive skin. She is incredibly skilled and adjusts the methods she uses based on what works. She’s top notch; can’t recommend enough.

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Dana Warby
August 26, 2023

Beautiful studio, lots of great services!

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Erika Chicas
August 25, 2023

Love this place and there snacks! Michelle is absolutely the best waxer ever! She has been waxing me for years and always leaves me with amazing results. (:

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Charlot Claudon
August 22, 2023

I recently had the RHA filler procedure done by Dr Brandy Segura. I had my lips, corners of my mouth and chin area worked on. I was numbed up before the procedure, which made it very comfortable. The procedure went very well,and I was very pleased with the filler used. It’s been three weeks now and I am very pleased with the end results.

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Leah Michelle
August 11, 2023

I love the space and the staff! Michelle does my facials lashes and brows. I absolutely enjoy my time with Studio R!

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Meredith Farmer
August 9, 2023

I decided to make a Brazilian waxing appointment at Studio R Aesthetics after a friend highly suggested them to me. I was not disappointed. The area is posh, welcoming, and luxurious. Michelle was patient with me as I asked questions and made sure I felt at ease during the wax. She was conversational enough to where I felt less tense, but not so much that I felt like I couldn’t enjoy the experience. I could tell she was very knowledgeable and she gave me a detailed 101 in sugaring vs. waxing. I’ve only dipped my toe into one small area of services here… they have so many more to offer! I’ll definitely be back!

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Lindsey Tennyson
August 7, 2023

What a tranquil environment! Walking into a very calm and clean reception area I was greeted almost immediately and taken back for my appointment fairly quickly. Michelle provided my services of a hydrofacial and waxing. Michelle was very professional and continued to educate me throughout the entire process. I learned so much about my skin and not only was rejuvenated but relaxed and at times, dozed off. I would highly recommend Studio R for any needs. All staff I came in contact with were friendly and beyond helpful.

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Sarah Snyder
August 3, 2023

I just recently moved (to Lynchburg) and was looking for an injector in a reasonable distance. I found Dr. Segura and loved the fact that she prefers to do the injecting work herself! I had Botox and fillers and when I asked about fillers she was very honest with me about what would help and make me happy. She didn’t try to sell me on more filler even when I thought it’s what I wanted! She was thorough, kind, and extremely gentle. And I’m obsessed with the results! Easily the best experience I’ve had! 10/10

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Janna P
August 3, 2023

Dr. Segura is fantastic. She has a wide range of minimally invasive options and during my initial consultation discussed the pros and cons of the treatments. I’ve had 2 of the 3 CoolPeel treatments that I purchased and I’m so happy with the results so far.

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Alexis Hamilton
August 2, 2023

If I could give 10 stars I totally would! For starters this office is GORGEOUS with an amazing vibe and quality music if I might add. Most importantly, Dr. Segura is AMAZING. Not only is she super kind and walks you through every step, but she listens to you and what YOU want and that is super important. I am OBSESSED with my lips and I plan to return for filler and other services in the future. You can tell Dr. Segura knows what she's doing & I love that 👏 The front desk staff were also super kind and did I mention, the office is BEAUTIFUL 🤩 I 100% recommend. If you're on the fence, do it! You won't regret it.

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Erich Arnold
August 1, 2023

Very thorough explanation of services and offerings, allowing the patient to come to an informed, personal decision as to their treatment. Excellent.

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Rose Vielandi
July 31, 2023

Dr Segura was extremely knowledgeable and helpful!

Every aspect of my experience at Studio R was amazing! The studio is incredibly clean and gorgeous - creating a relaxing, luxurious experience. All the staff are friendly, accommodating, and professional. My Botox and filler consultation with Dr. Segura was extremely informative and honest. This was my first time getting Botox/filler so she walked me through the basics, what to expect, pricing, areas of my face to prioritize over others, etc. She spelled everything out for me so there were no surprises! My Botox/filler combo appointment went extremely well. She made sure I was comfortable the entire time by checking in frequently. To her credit, it was a lot less painful than I anticipated due to the numbing cream and distraction device/methods she uses. It’s been a week since my appointment and I am SO happy with my results! She reduced my “gummy” smile with lip filler and also reduced TMJ related pain I was having with Botox. Studio R is a 1000 / 10!

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Lee Talbott
July 20, 2023

I am 75 years old and never thought it's possible to have that younger look. With the pleasant attention and treatment, I have received from the qualified staff, at Studio. R Aesthetics, It is possible. I am a happier 75-year-old and younger looking than before.

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Noman Vohra
July 18, 2023

My visit to studio R Aesthetics was great very clean environment and friendly staff. I went in for a chemical peel for my melasma and hyperpigmentation. Physician Michelle Morris took her time listening and explain me that it’s better if I wait not to get a chemical peel since I have rosacea. I like her honesty that she was worry about my skin rather than doing some procedure that I don’t need. So she recommended a facial which I really liked my skin felt much smoother and brighter main thing my rosacea did not flair up either after the procedure. All there products are great at the clinic she suggested to get some daily power defense moisturizer by zo which works great on my skin. I would Definitely recommend studio R.

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Mitchell Hubbard
July 18, 2023

I had my eyebrows tinted and shaped by Michelle. It was my first time having my eye brows professionally shaped and I was nervous. Michelle was wonderful and spend an hour and 20 minutes with me. I was so impressed and will make this a monthly part of my self care routine now.

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kbr3pz
July 2, 2023

I love how upscale and comforting this salon feels. Every team member I've worked with has been very happy to help me as well.

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Rebecca Leonard
June 24, 2023

Fabulous relaxing and restorative facial tailored just for my needed.

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Laquisha Taylor
June 17, 2023

The BEST in Charlottesville for lip filler and lash extensions! Dr. Segura and Michelle are so amazing to work with and my results are always perfection. I recommend Studio R to all of my friends and family.

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Claudia Gutierrez
June 17, 2023

I met with Dr. Segura to learn more about semglutide. The entire experience was lovely, their receptionist was super friendly and the office is beautiful. Dr. Segura was very informative and thorough.

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chelsea schafer
June 17, 2023

I love coming here! I’ve been coming here for the past year for a variety of things and have always had a positive experience.

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Lauren Girouard
June 17, 2023

Always a great experience at Studio R. Aesthetics!

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Jenny X
June 16, 2023

Dr. Segura is the best! She is very patient explaining all procedures to me carefully and thoroughly, and her results are terrific. I am often nervous before procedures and she is supportive of an incremental approach. Highly recommend.

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Tianna brown
June 15, 2023

Such an awesome staff!! So sweet and informative. I’ll definitely be coming back!

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Giles
June 12, 2023

Had a great experience at Studio R. Received a facial from Michelle who is an incredible aesthetician, and the front desk staff, Cat and Emily, were extremely friendly and courteous as well. 10/10 highly recommend!

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Brittany Grooms
June 10, 2023

Studio R Aesthetics is amazing! Michelle has been my go to for my waxing needs for many years and I’m super happy to have found this wonderful place. It’s absolutely gorgeous and welcoming. And everyone is so sweet! I had a facial done today with Michelle and it was hands down the BEST facial ever. 5 stars isn’t enough, I would definitely recommend!!

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Laurel Fortier
June 9, 2023

Amazing salon and very personable staff. Will absolutely return! Michelle was great and the sugaring process was as painless as possible!

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